Esomeprazole and Nexium are both prescription drugs for managing acid reflux disease (GERD) by targeting the same mechanism of action as Prilosec, a widely used prescription medication. Both drugs belong to the class of proton pump inhibitors (PPIs). They both work by reducing acid production in the stomach and esophagus, which helps reduce symptoms like heartburn and acid regurgitation.
Esomeprazole and Nexium are both prescription drugs for managing acid reflux disease (GERD). While esomeprazole is a proton pump inhibitor (PPI), Nexium is a prescription drug that is commonly used to manage acid reflux. Understanding the differences between these two medications is crucial for anyone considering these treatments.
| Medication | Proton Pump Inhibitor (PPI) |
|---|---|
| Esomeprazole | Prevents acid reflux by suppressing acid production in the stomach |
| Nexium | Supports acid regurgitation by reducing gastric acid secretion |
While both esomeprazole and Nexium are proton pump inhibitors (PPIs), their use requires careful consideration due to potential side effects like increased heart rate and increased risk of nephrotoxicity. Nexium, on the other hand, offers benefits like its longer half-life and reduced side effects compared to esomeprazole, making it a valuable option for managing acid reflux disease.
The dosage and administration instructions for Esomeprazole and Nexium are similar, with doses ranging from 30 to 60mg taken once daily. Typically, the starting dose is usually one tablet daily, but esomeprazole can be taken with or without food, as it dissolves in the stomach. For optimal results, the doctor may recommend the maximum daily dose for optimal acid control.
A study published in in the November 2017 issue ofJournal of the American Medical Associationfound that the use of Nexium, a proton pump inhibitor, can be associated with a high risk of cardiovascular events, particularly when used for long-term use. This study compared the risk of cardiovascular events in patients with and without a history of heart disease, according to published findings from a case-control study conducted among over 2,500 patients. Patients were randomly assigned to use either the Nexium or placebo for 7 to 14 days or a combination of both medications, which resulted in a difference of 5.2% in the incidence of cardiovascular events. Patients with a history of heart disease and those not taking the drug had a significantly higher incidence of the heart-related event (14% vs. 9%, P<0.001). Patients with a history of heart disease had a significantly lower incidence of cardiovascular events (14% vs. 6%, P<0.001).
A total of 5,907 patients with a history of heart disease and 1,892 without a history of heart disease were enrolled in the study. After 7 days of treatment, the patients were divided into 2 groups: those with and without a history of heart disease (N=5,067 and 1,842, respectively), and those without a history of heart disease (N=839 and 1,567, respectively). Compared with the non-users of the control drug, those with a history of heart disease had a significantly lower incidence of the heart-related (4.1% vs. 2.1%, P=0.002), and cardiovascular (2.4% vs. 3.0%, P=0.004) events compared with those without a history of heart disease. No differences were found in the incidence of the cardiovascular event between the 2 groups. Overall, the results suggest that the use of Nexium can be associated with a higher risk of cardiovascular events in patients with heart disease.
Nexium (esomeprazole magnesium) Capsules: Safety and Adverse ReactionsThe FDA has approved Nexium (esomeprazole magnesium), a proton pump inhibitor, as a drug that can be used for the treatment of reflux disease, ulcers, gastroesophageal reflux disease, and other gastric ulcers. Patients should be aware that Nexium can cause side effects such as heartburn, nausea, and diarrhea. Patients with stomach ulcers should discontinue use of the drug, as this can lead to complications.
The Nexium (esomeprazole magnesium) capsules are also indicated for the treatment of gastroesophageal reflux disease (GERD), which is a condition where the stomach becomes inflamed and the esophagus becomes weak. This is when symptoms of GERD appear in the upper esophagus. Patients should discontinue the use of Nexium, if they have GERD. To avoid any long-term damage to the esophagus, it is advisable to take this medicine for at least three months to allow the esophagus to heal properly.
The use of Nexium in the treatment of heartburn and other acid-related problems is also contraindicated. Patients with history of stomach ulcers should discontinue the use of Nexium, as this can lead to complications such as heartburn and gastric problems.
The Nexium (esomeprazole magnesium) Capsules: Side Effects and ContraindicationsThe safety and effectiveness of the Nexium (esomeprazole magnesium) capsules have been established in over 10,000 patients with gastroesophageal reflux disease (GERD) and other conditions.
Nexium (esomeprazole magnesium) Capsules are indicated for the treatment of reflux, heartburn, acid reflux, and other conditions affecting the stomach. Patients who have heartburn or other gastrointestinal problems should discontinue the use of Nexium, as this can lead to complications such as heartburn and gastric problems.
The Nexium (esomeprazole magnesium) Capsules are contraindicated in patients who have taken any form of NSAIDs, including Nexium, for several days or weeks at a time, as this can lead to complications such as heartburn, gastric problems, and ulcers.
The Nexium (esomeprazole magnesium) Capsules are also indicated for the treatment of acid reflux, reflux, and ulcers.
The Nexium (esomeprazole magnesium) Capsules are contraindicated in patients who have taken any form of NSAIDs for several days or weeks at a time, as this can lead to complications such as gastric problems, ulcers, and heartburn.
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June 26, 2024Reported Price History
As of 2024, the average retail cost of Nexium 40 mg (esomeprazole magnesium) 40 mg tablet is around $3.23 for a supply of 60 tablets. This cost does not include shipping costs and any other costs related to your package. Nexium 40 mg is available in capsule form and comes in tablet form.
Nexium 40 mg (esomeprazole magnesium) 40 mg tablet is an antacid salt and acid salt that works by preventing the ester group of medicines from esterifying with stomach acid. This helps to prevent stomach acid from entering the esophagus and causing an esophageal sphincter (ESS) ulcer. Nexium 40 mg tablet is also used to treat gastroesophageal reflux disease (GERD) in patients with heartburn, ulcers, or GERD.
The price of Nexium 40 mg in Pakistan is around $5 for a 30-tablet capsule of 20 mg (40 mg) of the salt.
This product may be marketed under various brand names, including Prilosec, Nexium, Nexium Capsules, Prilosec ER, and Prilosec USP. Consult with a pharmacist or doctor before using this or any other product for any health condition.
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Alternate Name:Pharmapure RX Esomep-EZS
Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.
Dosage Form:Capsule Delayed Release
Administration Route:By mouth
Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent
Generic Available:Yes
Strength:20 MG
Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools
Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.
You should know how to use esomeprazole if you have trouble swallowing food.You can get esomeprazole for less than $1 for a supply of 30 capsules. You can also buy esomeprazole online from AstraZeneca. You can also find esomeprazole for less than $1 for a supply of 30 capsules. You can easily place an appointment with your doctor at which you can get a prescription for esomeprazole capsules 40 mg.You can buy esomeprazole over the counter at participating pharmacies near you to get a typical Nexium discount of up to 80% off the retail price at all selling participating pharmacies near you.You can find esomeprazole for less than $1 for a supply of 30 capsules. You can also buy esomeprazole over the counter at participating pharmacies near you.Details
Nexium Control provides a course of treatment for relieving symptoms of heartburn, indigestion, and acid reflux. Each pack contains 7 tablets intended for short-term use. These tablets work by reducing stomach acid production, thereby managing discomfort associated with digestive acid-related conditions. It's important to follow the instructions provided for optimal results. GlaxoSmithKline (UK) Trading Limited GSK Consumer Healthcare (IE) Ltd., 980 Great West Road, Brentford, TW8 9GS, U. K. Or: 12 Riverwalk, Citywest Business Campus, Dublin 24, Ireland.
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Ingredients
Ingredients: Each Gastro-Resistant Tablet contains 20 mg Esomeprazole (as Magnesium Trihydrate). Contains sucrose. See package leaflet for further information. As we are always looking to improve our products, our formulations change from time to time, so please always check the packaging before use.
Directions
Directions for use: Take one tablet once a day. Do not exceed this dose. The tablets should be swallowed whole. Do not chew or crush the tablets. May take 2-3 days for full effect. If your symptoms worsen or do not improve after taking this medicine for 14 days in a row, contact your doctor. Read the package leaflet before use. Oral use. Storage recommendation: Do not store above 30°C. Store in the original package in order to protect from moisture. Keep out of the sight and reach of children.
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